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In an initial study of switching smokers to research cigarettes with very low nicotine content [34], participants were asked to smoke their usual brand of cigarettes and one of five research cigarettes with varying nicotine contents in a progressive manner (range: 12 to 1 mg/cigarette)

If your home tends to be humid, consider running a dehumidifier in the room where cones are kept

Notably, this study provides high-certainty evidence for the first time that such interventions also work for pregnant individuals