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Table 2 Characteristics of participants of the 71 included Cochrane reviews In terms of interventions, the included SRs involved various approaches such as pharmacotherapy (24 SRs), non-pharmacological therapy (31 SRs), mass media (2 SRs), traditional Chinese medicine (TCM) therapy (1 SR), policy (5 SRs), other support (6 SRs) and combinations of different therapies (12 SRs)

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Response : The present rat-to-human translational study demonstrates the efficacy of a combination of UCS memory retrieval and propranolol for inhibiting nicotine craving induced by exposure to diverse nicotine-associated CSs and nicotine itself.The findings across species suggest that the UCS-induced memory retrieval-reconsolidation interference procedures are more promising for prevention of relapse to drug use than the CS-induced procedures