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In lower-cost models, replacement may not be practical

Proven population-based measures include increasing the price of tobacco, implementing comprehensive smoke-free policies, implementing hard-hitting media campaigns, and increasing access to cessation services. Beyond this, other strategies advocated by the World Health Organization as part of its MPOWER measures include monitoring tobacco use and prevention policies and enforcing bans on tobacco advertising, promotion, and sponsorship

However, the validity of RECIST has been questioned in the context of targeted therapies and immunotherapies due to phenomena such as pseudoprogression 100

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doi: 10.1136/bmj.l5275 Summary Keywords E-cigarettes, health effects, tobacco harm reduction, chronic effects of vaping, systematic review Citation Izquierdo-Condoy JS, Naranjo-Lara P, Morales-Lapo E, Hidalgo MR, Tello-De-la-Torre A, Vsconez-Gonzles E, Salazar-Santoliva C, Loaiza-Guevara V, Rincn Hernndez W, Becerra DA, Gonzlez MBD, Lpez-Corts A and Ortiz-Prado E (2024) Direct health implications of e-cigarette use: a systematic scoping review with evidence assessment