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Nicotine, the primary addictive component of tobacco, acts on nicotinic acetylcholine receptors in the brain, leading to the release of dopamine and other neurotransmitters associated with pleasure and reward

The costs of gun violence Anti-gun advocates have long called for the firearm industry to lose the special treatment it receives, given the harms that firearms cause

PMC 2563625

In the meantime, local and state level protections including prioritizing tobacco program spending in existing budgets, higher tobacco excise taxes on tobacco products, stronger local tobacco policies supporting smoke-free environments, and restrictions on the sale of flavored tobacco products are needed to address long-existing inequities in smoking rates and health outcomes in our country

Lake James, a power-generating reservoir in western North Carolina, is named for him