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Smoking-induced microbial dysbiosis impacts multiple anatomical sites, including the oral cavity, respiratory tract, and gastrointestinal system, driving disease progression through mechanisms such as immune modulation, chronic inflammation, and metabolic dysregulation

These lower-dose nicotine gum tablets are typically recommended for individuals who smoke fewer than 25 cigarettes a day or for those who have a preference for a gradual reduction in nicotine intake during their smoking cessation journey

Proceedings of the Royal Society of Canada 2002 Symposium on Addictions: Impact on Canada

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Several countries are increasingly implementing strategies to tighten their tobacco policies in the hopes of deterring smoking, especially among young people