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Clemmons DR, Miller S, Mamputu JC: Safety and metabolic effects of tesamorelin, a growth hormone-releasing factor analogue, in patients with type 2 diabetes: A randomized, placebo-controlled trial

These serve to increase dendritic surface area and biochemically isolate individual PSDs

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Assuming Eli Lilly follows a similar timeline to tirzepatide, the earliest possible FDA approval for retatrutide would likely occur in late 2027 or 2028, depending on Phase 3 trial results and regulatory review timelines

J Cosmet Dermatol