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Your hands and feet develop tingling or numbness that feels like pins and needles, while your tongue becomes swollen, red, or unusually smooth

B-12 helps maintain the health of the nervous system and supports proper brain function and is required for the synthesis of DNA, the genetic material present in all cells playing a crucial role in cell division and growth

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In addition, PD target levels were determined based on preclinical data to allow an assessment of the relevance of the administered doses in terms of target inhibition during the Phase I clinical study and to determine the RP2D

The physiological and uptake experiments suggested that Seo1p must be present at the plasma membrane