Pomalidomide-C2-alkyne halide [O-]C(=O)C1=CC(=CC=C1C1=C2C=C3CCC[N+]4=C3C(CCC4)=C2OC2=C3CCCN4CCCC(C=C12)=C34)C(=O)NCC#C Purity (HPLC): ≥ 95%

[O-]C(=O)C1=CC(=CC=C1C1=C2C=C3CCC[N+]4=C3C(CCC4)=C2OC2=C3CCCN4CCCC(C=C12)=C34)C(=O)NCC#C Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

458 SMILES [N-]=[N+]=NCCOCCOCCOCCOC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name Phthalimidinoglutarimide-C3-O-PEG4-OH Synonyms Phthalimidinoglutarimide-4'-C3-O-PEG4-OH CAS Number n/a Related CAS Molecular Formula C24H34N2O8 Molecular Weight 478

NCCCCCCCC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

S)-AHPC-CO-PEG1-C2-Cl Synonyms CAS Number n/a Related CAS Molecular Formula C27H37ClN4O5S Molecular Weight 565

Pomalidomide-C2-alkyne halide [O-]C(=O)C1=CC(=CC=C1C1=C2C=C3CCC[N+]4=C3C(CCC4)=C2OC2=C3CCCN4CCCC(C=C12)=C34)C(=O)NCC#C Purity (HPLC): ≥ 95%Degrader building block for targeted protein degradation. Contains an E3 ligase ligand with a linker and a function group, which can be conjugated to target protein ligands through straightforward chemical reactions. Product Name Pomalidomide C2 alkyne Synonyms Pomalidomide 4' C2 alkyne CAS Number 2154356 73 5 Related CAS Molecular Formula C17H15N3O4 Molecular Weight 325. 324 SMILES O=C1N(C2CCC(=O)NC2=O)C(=O)C2=C(NCCC#C)C=CC=C12 Purity (HPLC) >= 95%