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each case is judged individually.11 Solid evidence on the safety of parenteral, lifelong, high dose hydroxocobalamin is available from decades of treating patients with inborn errors of B 12 metabolism (eg, cobalamin C deficiency).6768 Symptom monitoring Monitor symptoms regularly (eg, every two to three months) as they may reappear, even after several months, if injection frequency is reduced

We will ask about this at consultation and coordinate with your GP where appropriate

It has no FDA-approved indication or established human dosing regimen

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