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Research demonstrates that various iron metabolism-related genes regulate ferroptosis processes, including transferrin, nitrogen fixation system 1 (NFS1), iron-responsive element-binding protein 2 (IREB2), nuclear receptor co-activator 4 (NCOA4), solute carrier family 7 member 11 (SLC7A11), and glutathione peroxidase 4 (GPX4)each representing key genetic determinants of ferroptosis susceptibility (62, 63)

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Berry SH, Elliott MN, Suttorp M et al: Prevalence of symptoms of bladder pain syndrome/interstitial cystitis among adult females in the united states