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It also ameliorates AD-related phenotypes by restoring hippocampal gene expression signatures (257)

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Consequently, the balance between H3K27me3 and H3K4me3 is disrupted, leading to an overall shift in the epigenetic state toward gene suppression

doi: 10.1016/j.ejmech.2019.111631

Inhibition of CPT I should cause an increase in long-chain acyl-CoAs in the cytosol