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Mitochondria-targeted antioxidants: a step towards disease treatment

The colonization of the obese microbiota in germ-free mice resulted in a more significant increase in total body fat compared with the colonization of the lean microbiota 105

Following the above general procedure C, the reaction was purified by flash-column chromatography on silica gel to provide the desired ethyl 4-(adamantylamino)-3-(pyrimidin-5-ylmethylamino)benzoate (SRS16-41, Scheme 3) (80 mg, 0.197 mmol, 80%)