ipamorelin is it safe What are the downsides of Ipamorelin? CJC-1295 / Ipamorelin Peptide Therapy:

Essential thrombocythemia typically presents with vasomotor symptoms like erythromelalgia (burning pain and erythema of the hands and feet), headache, and an increased risk of thrombosis

Its not always safe

Qiu K, Mao M, Deng D, Jiang C, Li L, Zheng Y, Ren J, Zhao Y

J Neuroimmunol 34:159164 Choi IY, Piccio L, Childress P, Bollman B, Ghosh A, Brandhorst S, Suarez J, Michalsen A, Cross AH, Morgan TE, Wei M, Paul F, Bock M, Longo VD (2016) A diet mimicking fasting promotes regeneration and reduces autoimmunity and multiple sclerosis symptoms

As a person loses weight, their resting metabolic rate falls below what their new body weight would predict