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Importantly, electron microscopic observation revealed that HG-induced mitochondrial damage of ferroptosis in HK-2 cells was characterized by the disappearance of mitochondrial cristae and rupture of the mitochondrial membrane, which was significantly attenuated by Cur-NCs and Fer-1 treatment (Figure 2C)

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Exogenous 5-MTP improves endothelial repair, reduces vascular permeability, and prevents intimal hyperplasia in aging models [186]

doi: 10.1016/j.jss.2005.05.028 21 LimJSLeeSHYunHLeeDYChoNYooGet al