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In the past, efforts were concentrated on CPT1A inhibitors, primarily two main kinds of inhibitors including substrate derivatives, glycidic acid derivatives, and malonyl-CoA analogues (Figure 9) ( FIGURE 9 Etomoxir and 2-tetradecylglycidic acid (TDGA) are both ethylene oxide compounds

Cell death inhibitors were used at the following concentrations 10M Q-VD-Oph (AdooQ Bioscience, #A14915-25), 20M -tocopherol (Merck, #258024), 2M Ferrostatin (Merck, #SML0583), 65M L Cystine (Medchemexpress, #HY-N0294) or 30nM Sodium selenite (Merck, # S5261) and supplemented to cell culture at the same time of the cytotoxic agents

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The experiment began with a cell density of 2.20 104 cells/mL of M

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