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Structure and function of ABCG2-rich extracellular vesicles mediating multidrug resistance

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ROS and oxidatively modified macromolecules function as damage-associated molecular patterns (DAMPs), engaging pattern recognition receptors (PRRs) on microglia, including Toll-like receptors (TLRs) and NOD-like receptors (NLRs), to initiate inflammatory cascades (Block et al., 2007)

[55] Different NMR experiments have varying degrees of timescale sensitivity that are appropriate for different protein structural changes

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