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Preventive Effect of Different Citrus Essential Oils on Primary Dysmenorrhea: In Vivo and In Vitro Study

It appears that extensive oxidation of polyunsaturated fatty acid (PUFA)-containing phospholipids might modify membrane structure and increase membrane permeability, eventually resulting in plasma membrane rupture in response to accumulation of lipid-ROS, e.g., lipid hydroperoxides

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In addition to several solvent molecules, the initial FoFc electron density map revealed clear density that could not be satisfactorily explained by buffer components present during purification and crystallization (Tris, citrate, glycerol, DTT) and was most consistent with a phospholipid-like molecule

Tolerance is a physiological state characterized by a reduced response to a drug after repeated administration (i.e., a higher dose of a drug is required to produce the same effect that was once obtained at a lower dose)