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Studies have shown that the AKT inhibitor ipatasertib (Ipa) combined with TMZ, can significantly increase ferroptosis in IDH-mutant glioma cells ( Boric acid enhances the chemosensitivity of TMZ-resistant GBM cells by activating the ferritin autophagy pathway and disrupting cellular iron homeostasis

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Catalase (CAT) and glutathione peroxidase (GPH) catalyze the breakdown of hydrogen peroxide and lipid hydroperoxides, respectively, thereby preventing the formation of additional reactive oxygen species

Most people get enough B12 from their diet, but many have absorption issues that mean adequate intake doesnt translate into adequate cellular levels

doi: 10.1038/s41420-023-01773-8 Summary Keywords B cell, ferroptosis, immune modulation, macrophages, microglia, ocular microenvironment, T cells Citation Zhu G, Lin Y, Han Z, Cao H, Zhu K, Shi R, Deng Y, Li S, Yang Q and Lu X (2026) Ferroptosis and the eye: bridging the gap between cell death and vision preservation