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470 In animal models of Apelin-13-caused cardiomyocyte hypertrophy and heart failure, NCOA4-activated ferritinophagy leads to the upregulation of SFXN1 expression, causing mitochondrial iron overload and mitochondrial ROS overproduction, increased lipid peroxidation, and ultimately, ferroptosis

However, the total amount of calcium in LZG serum was significantly increased compared with NZG and PZG (Fig

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Hydroxylation is the predominant metabolic pathway in early neonatal life, whereas glucuronidation increases as UGT1A9 activity matures postnatally (119, 202)