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Inflammatory cytokines may be produced by mononuclear cells of the immune system in response to numerous agents, such as microorganisms and their products (e.g., lipopolysaccharide LPS)15,16 as well as some xenobiotics.17 It is postulated that xenobiotics can influence the concentrations of inflammatory cytokines through oxidative stress mechanisms.1820 The experimental and epidemiological data currently available to evaluate the above toxigenic risks of aspartame are insufficient and often unreliable, due to the inadequate planning and conduct of previous experiments

10.1210/jc.2006-1702 20 JastreboffA

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We often turn to exotic or rare herbal extracts for this, such as Spermidine or Ashwagandha, as these supplements are supported to promote anti-ageing, health and well-being