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168 Recent studies also show that knocking down PPAR coactivator 1 (PGC1), an important transcriptional coactivator regulating CPT1A and CPT1B, obviously decreases the ratio of NADPH/NADP + and ATP levels, impairing radiation resistance in nasopharyngeal carcinoma (NPC) cells

Nature 539 , 443447 (2016)

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NADPH-dependent NDB1 (NPDex) and NADH-dependent NDB2-NDB4 (NDex) are located on the outer surface of the inner mitochondrial membrane (Schertl and Braun, 2014