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The Large Folate Cycle The large folate cycle consists of three substances: Tetrahydrofolate (THF) 5, 10-Methylenetetrahydrafolate Methylfolate (5-MTHF) The folate cycle is responsible for converting tetrahydrofolate (THF) into initially 5, 10-methylenetetrahydrafolate and finally methylfolate (5-MTHF)

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Karczewski J, Troost FJ, Konings I et al (2010) Regulation of human epithelial tight junction proteins by Lactobacillus plantarum in vivo and protective effects on the epithelial barrier