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*Correspondence: Niteen A

Studies evaluating the impact of ecologically relevant levels of dLAN (5 lux) have reported that stroke lesion size was significantly larger in dLAN mice compared to mice housed in dark nights after 24 h (Weil et al., 2020)

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A: Epithalon is derived from activity in the pineal gland region, which also produces melatonin

Furthermore, when combined with low doses of propofol, Dex significantly inhibited inflammatory responses, oxidative stress, and neuronal apoptosis in the hippocampal region of developing rats [192]