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Beyond nanoformulations, other innovative delivery strategies have been investigated to further enhance curcumins pharmacokinetic and pharmacodynamic properties

Alagoz G, Celiker U, Ilhan N, Yekeler H, Demir T, Celiker H

Despite the role of gut microbiota in the modulation of dopamine and norepinephrine remains to be fully understood, germ-free (GF) animal models have shown that there is a noteworthy alteration of these neurotransmitters in the gut as well as in the brain, which could have important consequences in the behavior [178]

It is possible that these differences are explained by cell typespecific differences, or the ability of p21 to regulate redox homeostasis via alternative means in some contexts (Chen et al, 2009)

Qiao Y, Su M, Zhao H, Liu H, Wang C, Dai X, Liu L, Liu G, Sun H, Sun M, Wang J, Li Z, Fan J, Zhang Q, Li C, Situ F, Xue J, Jia Z, Zhang C, Zhang S, Shan C