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10.1038/s41568-022-00459-0 84 LiF.-J.LongH.-Z.ZhouZ.-W.LuoH.-Y.XuS.-G.GaoL.-C

confirmed an average increase of 1025% in the activity of AChE and BuChE in the presence of Epitalon in the medium

Although these therapeutic strategies are still in development, they have the potential to suppress ALS progression by directly targeting specified glial cell populations, applying Treg, and suppressing age-associated chronic inflammation (Gendron and Petrucelli, 2023)