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Natelson and others, Shungu, from 2009-2017 demonstrated in a series of five studies that lactate was increased and glutathione decreased in the brains (ventricles) of people with ME/CFS

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Accumulating in-vitro and in-vivo data show that ferroptosis not only participates in OSCC initiation and progression but is also closely associated with immune escape, chemoresistance, and poor prognosis

Macrophage activation and foam cell formation may explain the elevated CRP serum levels and contribute to disease progression (Figure 3)