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These effects of T 4 have been confirmed in various models of neurological damage, such as spinal cord injury, traumatic brain injury (Xiong et al

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For the next stage of this study, the primary goal shifted to designing naphthylcombretastatin-based prodrugs that can be effectively converted in vivo to the bioactive drug 20 (Fig

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Other studies have also shown that chronic administration of rotenone over a long period can increase nitric oxide and lipid peroxidation products in the brain cortex and striatum in rats, which then clearly mimic parkinsonian behavioral symptoms such as akinesia and rigidity

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Marshburn et al

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