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10.1016/j.ecoenv.2019.03.089 Ecotoxicol Environ Saf

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After 20 to 30 minutes, remove the patch and gently let it absorb

Moreover, long Lyme patients are familiar with the Jarisch-Herxheimer Reaction, a potentially intense inflammatory response, which can be elicited by an antibiotic treatment of a persistent borreliosis (138)