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Continued use for 34 weeks improves pigmentation and uneven tone further

DILI drug-induced liver injury, AP antipsychotic, FGA first-generation antipsychotic, SGA second-generation antipsychotic, ALP alkaline phosphatase, N/A not addressed a Chlorpromazine therapy combined with olanzapine b Patient previously treated with risperidone Atypical, second-generation antipsychotics (SGA), including clozapine, risperidone, olanzapine, and quetiapine, are available since the 1990s

In autophagy-deficient cells, SQSTM1-induced Nrf2 activation is critical in tumor progression (Komatsu et al., 2010)

Andleeb M, Shoaib Khan HM, Daniyal M

In ovarian cancer, hypoxia results in CCL28 upregulation, leading to a robust increase in Treg infiltration, VEGF and blood vessels, whereas depletion of Tregs reduces intratumoral VEGF levels and tumor angiogenesis 18,81