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Excavation of a 5,300 year-old mummy, called an Iceman, confirmed that our ancestors also suffered from B

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Moreover, manipulation of the activity of mTORC1 by TSC2 knockout increased the expressions of ERO1, IL-6, p-STAT3, and SLC7A11 in TU177 cells (an LSCC cell line with moderate mTORC1 activity) (Supplementary Fig