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SNRIs increase the activities of serotonin and norepinephrine (also called noradrenaline) by interfering with their transport once they are released

2.8 Altered iron metabolism Iron accumulation is reportedly a mechanism that can lead to cellular damage in both neurodegeneration and metabolic dysfunction models, and iron-dependent programmed cell death (ferroptosis) is observed in both conditions ( Ferroptosis has been recently investigated as one of the iron-dependent mechanisms that most intervene in cell death in metabolic dysfunctions and PD

These studies illustrate that broccoli seeds induce antioxidant and detoxification proteins in a NRF2-dependent manner

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Efficacy of a plant-microbe system: Pisum sativum (L.) cadmium-tolerant mutant and Rhizobium leguminosarum strains, expressing pea metallothionein genes PsMT1 and PsMT2 , for cadmium phytoremediation