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The decomposition of hydroperoxides into radical species requires high energy input which is mediated by metal catalysts

O'Shaughnessy PJ, Antignac JP, Le Bizec B, Morvan ML, Svechnikov K, Sder O, Savchuk I, Monteiro A, Soffientini U, Johnston ZC, Bellingham M, Hough D, Walker N, Filis P, Fowler PA

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5.2.2.2 Parkinsons Disease On the frequency ranking for neurodegenerative diseases, Parkinsons Disease (PD) follows AD at second place and is characterized by the accumulation of -synuclein in neurons, glial cells, and nerve fibers (279)