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The symptoms of B12 deficiency can vary widely and may include fatigue, weakness, tingling or numbness in the hands and feet, difficulty concentrating, and even mood disturbances

These offer a triple-action approach for short, mid and long-term skin renewal benefits

2013) was not upregulated, while the expression of GLXIII (At3g54600), encoding an enzyme of low in vitro activity on methylglyoxal, was upregulated by factor 2 and 4 in A12 and At22, respectively (Table 3)

However, EGCG is highly susceptible to degradation in the body, and its stability and bioavailability after oral administration are insufficient, limiting its application in rectal radioprotection [16,17,18]