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Results: Analysis of hepatic mRNA transcriptome revealed upregulated expression of genes associated with the mitochondrial tricarboxylic acid (TCA) cycle and mitochondrial envelope in NAFLD patients, who exhibit characteristic mitochondrial dysfunction

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These are considered an alternative treatment to metformin, as their function lies in the modulation of the components that signal the insulin pathways, thus influencing processes such as the regulation of the menstrual cycle, carbohydrate metabolism, and hyperandrogenism