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Microarray profiling of isolated abdominal subcutaneous adipocytes from obese vs non-obese Pima Indians: increased expression of inflammation-related genes

Senescent mitochondria not only produce more ROS due to inefficient electron transport but also exhibit impaired iron-sulfur cluster biogenesis, leading to improper iron handling and accumulation within the mitochondria, thus creating a potent internal source of oxidative stress (106,107)

Symptoms may include fatigue, weakened immunity, frequent illness, poor skin health, or even slow recovery from stress or toxins

We therefore used female animals in our study

This process is vital for skin health as free radicals can be induced by sun exposure, pollution, or smoking