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Direct anabolic signaling certain peptides, notably IGF-1 LR3, act directly on muscle tissue at the receptor level to stimulate protein synthesis and satellite cell (muscle stem cell) proliferation and differentiation the fundamental cellular process of muscle growth

Exposure to extreme temperatures, both hot and cold, puts the stability of benzyl alcohol at risk

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Intralesional administration.When the strength and dosage form of the drug lend the preparation to the treatment of the condition, those products labeled for intralesional administration are indicated for: Keloids Localized hypertrophic, infiltrated, inflammatory lesions of: lichen planus, psoriatic plaques, granuloma annulare, and lichen simplex chronicus (neurodermatitis) Discoid lupus erythematosus Necrobiosis lipoidica diabeticorum Alopecia areata They also may be useful in cystic tumors of an aponeurosis tendon (ganglia)