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From the SwissADME, the accessibility of glutathione-epothilone conjugate was completely diminished as a P-glycoprotein substrate, unlike to the higher feasibility of epothilone, ensuring the molecular structural change of the compound by Glutathionylation

Whether they are natural compounds, small molecule antioxidants, or large molecule antioxidant enzymes, when modified with nanomaterials, they all exhibit higher cell uptake rates and stability

10.1097/CHI.0b013e318195bd15 245 HalseyL

Therefore, further analysis of docking poses of both wild and mutant protein was performed

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