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However, the binding of miR-1 to mitochondrial transcripts has been suggested only by Ago2 CLIP experiments, and to date, miR1 is the only example of this non-canonical mitomiR function

Schmaal L, Berk L, Hulstijn KP, Cousijn J, Wiers RW, van den Brink W

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Recently, it has been demonstrated that inhibition of GDF15 counteracts cachexia by reducing activation of sympathetic nervous system on adipose triglyceride lipase (ATGL) and hormone-sensitive lipase (HSL) in WAT, highlighting its major contribution in cachexia development besides appetite regulation (Suriben et al., 2020)

& Mori, H