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Even in participants whose contralesional arm performed within the normal range on the VGR task, we observed a bias towards using the ipsilesional arm on the OH task ~30% of the time (Hand hits bias: 20-34%, Hand speed bias: 16-35%, Movement area bias: 11-27%)

Further supporting evidence comes from a pan-cancer meta-analysis of over 1,000 patients treated with ICIs, where a machine-learning model integrating genomic, immune, and clinical variables identified male sex as a significant positive predictor of response [124]

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