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Participants received either 83 g (3,332 IU) vitamin D daily for 1 year (n = 31) or placebo (n =2 3)

Vitamin D has been shown to induce a decrease in the production of pro-inflammatory cytokines including IL-1, IL-6, and TNF, and an increase in the secretion of the anti-inflammatory IL-10 [43,44,45,46,47,48,49,50]

9 The RTA capacity to block peroxyl radicals was later attributed to the liproxstatins quinaxoline ring

The comprehensive data resources in the EDW enabled accurate scoring and automated score calculations

For future studies, it is recommended to select earlier time points and a higher frequency to assess gene expression and mitochondrial functionality of PBMC following an LPS challenge, as the primary dynamics of the immune response occur immediately after the immune challenge