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10.3390/molecules23112983 92 SunC.LiS.LiD

It is also important to recognize the common problems of sanitization process, the causes of sanitization failures and how to troubleshoot and take remedial actions with respect to material, construction methods, biofilm removal process and timing of sanitization

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Exposure of human lung epithelial (A549) cells to acrolein (150 fmol/cell for 1 h) first depleted 80% of the intracellular GSH pool and then increased the transcription of -glutamylcysteine synthetase at 6-12 h post-treatment, resulting in normalization of GSH levels

Furthermore, pyruvate dehydrogenase complex can translocate from the mitochondria to the nucleus (in a manner still unclear) during cell-cycle progression, generating a nuclear pool of acetyl-CoA from pyruvate and increasing the acetylation of core histones important for S phase entry as well as expression of damage-response genes among others (82