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Although the disease usually does not affect the patients intellect or senses at early stage, it may eventually lead to generalized paralysis, the impairment of multiple nervous systems and the loss of respiratory function

Finally, well-controlled human studies investigating this axis remain scarce, with most insights derived from animal models

During the progression of the disease, the size of the thyroid gland May decrease or remain normal, according to fibrosis extent

Ca2+/calmodulin-kinase II enhances channel conductance of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate type glutamate receptors

Luo C, Sun J, Sun B, He Z