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The nuclear SUMO-targeted ubiquitin quality control network regulates the dynamics of cytoplasmic stress granules

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Weve shown these cells reach the brain intact. Two pathways make this possible: The Olfactory Pathway: Provides rapid, direct access to the brain through extracellular transport, with therapeutic agents reaching the olfactory bulb within minutes of administration

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EVs, extracellular vesicles

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Organelles such as mitochondria, the ER, and the GA exhibit diurnal rhythmic changes in their structures [209,210,211], suggesting that their ROS-generating capacity may also undergo periodic variations

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