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Our model simulations are reflective of the hepatic GSH environment, agreeing with the supra-pharmacological concentrations of doxorubicin required to illicit comparable GSH depletion in the liver 39

For treatment of people who become infected with COVID-19, higher vitamin D3 doses might be useful ( Figure 3 Concerning the global deficiency of vitamin D, particularly in the Northern Hemisphere populations during the winter, dietary vitamin D supplementation (5,000 IU daily) could have positive outcomes for high-risk groups of individuals (diabetes and obesity), but also during quarantine ( 12 , has been reported ( Such defects take place even in high-income countries and are the most common among children and infants, adolescents, the elderly, and during lactation and pregnancy (Table 1