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Upon short H 2 O 2 -induced and t-BOOH-induced oxidative insult, a detectable, but not significative, decrease in GSH was measured in untreated or NAC-treated cells, while a much more important and significant decrease was observed in NACET-treated cells

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For example, SASP profiles from iron-induced senescent endometrial cells in endometriosis may differ from those in fibroblasts undergoing telomere-related senescence

In addition to the above mechanisms, activation of the cGAS-STING pathway in tumor ECs also impacts their metabolism