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In this case, intracellular integrin signalling could be important

Tamai, K., Satoh, K., Tsuchida, C., Hatayama, I., Maki, T

Although the dextran/gelatin hydrogel is mechanically weak as an NP implant, the aldehyde groups in the material could react with the tissue surface, causing the hydrogel to adhere to the tissue surface by a covalent connection, preventing encapsulated MSCs from leaking out (Sakai, 2008)