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Levobupivacaine, distinct from its anesthetic effect, inhibits SLC7A11/GPX4 and promotes p53-mediated ferroptosis to exert an antitumor effect in non-small cell lung cancer (Meng et al., 2021)

Those who started on a placebo and switched to Kesimpta in the extension trial also experienced pronounced reductions in their relapse rates and MRI lesions, and their NEDA-3 rates increased after switching as well