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Despite this uniform increase in GFR, variations in renal tubular transport (either secretion or reabsorption) can produce different effects on renally cleared drugs (Muller et al

Available from: Sabatino A, Fiaccadori E, Barazzoni R, Carrero JJ, Cupisti A, De Waele E et al

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Many studies have questioned if an increase in maternal folate during pregnancy, with the main aim of reducing neural defects, could somehow be related to an increased risk of ASD in children because the timing of neural tube closure, and therefore the use of folic acid corresponds with embryogenesis

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