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When ROS levels rise beyond control, oxidative stress increases and begins to disrupt normal cell function

Given these cells are also CD4 + T cells like those studied by Ghergurovich et al., it is possible that production of these cytokines is impaired like their T h 1 counterparts

10.3390/nu13113960 Nutrients

The bipyridyl herbicide paraquat produces oxidative stress-mediated toxicity in human neuroblastoma SH-SY5Y cells: relevance to the dopaminergic pathogenesis