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and ii) direct effects on GPX4, including oxidative damage to its structure, genetic alterations affecting its expression and functionality and the use of specific pharmacological inhibitors (148150)

doi: 10.1210/en.2008-0816 236 CamporezJPGJornayvazFRPetersenMCPestaDGuigniBASerrJet al

E., Wasdell, M

BER plays a crucial role in mitigating DNA damage caused by endogenous and exogenous mutagens, ensuring the maintenance of sperm quality and preventing premature aging, cancer, and infertility